Lab news

2024​​

• November 15, 2024, Charity, Chitra, Nassim, Sarah-Maude, and Yousra present at the 2nd Canadian Peptide and Protein Community virtual meeting (https://sciforum.net/event/2ndCPPC#instructions?section=#sessions).     

• December 3rd, 2024, Dr. Xiaozheng Wei presents successfully her doctoral thesis

• CD36 modulators show efficacy in hind limb ischemia-reperfusion  (DOI: 10.1002/jbt.70057).  

• Canadian receives the 2024 Murray Goodman award of the American Peptide Society (https://americanpeptidesociety.org/award/lubell-william/)      

• Chromatography-free cholesterol supported synthesis has been innovated by Nassim, who made betaines and organic cations see Organic Letters (DOI: 10.1021/acs.orglett.4c03336) !

• Kajumee spoke about dual targeting anti-parasitic agents at QOMSBOC 2024 in Toronto : https://www.qomsboc.ca/

• Justin wins Roger Barré and Steve Hanessian Awards !

• Kinshuk begins Ph.D. studies.

• Bill, Nassim, Debora, Xiaozheng, Charity and Yousra will attend the 37th European Peptide Society Symposium (https://eps2024.com/) !

• Between the folds at FOLDAMERS 2024 on NYU campus, June 19 – 21, 2024 (see image), Bill presented "Folding into Chiral Space Without Stereogenic Carbon” featuring recent insights gained by Xiaozheng.​​​​​​​​​​​​​

• Novel sheet! Stabilization of macrocyclic antimicrobial peptides based on the pioneering studies of Becker and Naider on lactams and turns. See: Journal of Medicinal Chemistry (DOI: 10.1021/acs.jmedchem.4c00005).

• A preprint of our review on benzotriazepines is now online! Kudos to undergraduate student Sarah Maude Harvey, who piloted this overview of the privileged structure in the Canadian Journal of Chemistry (DOI: 10.1139/cjc-2023-0146) !

• Bill gave the lecture "Inspired by Morten and the other hand of tryptophan”  at the Morten Meldal Symposium 2024: https://eventsignup.ku.dk/mortenmeldalsymposium2024/conference !​​​​​

• Congratulation to Justin Desjardins-Michaud on receiving an NSERC graduate student scholarship.

• In May, we welcome Ph.D. student Debora Iaculli from the lab of Professor Steven Ballet at the Vrije Universiteit Brussel, Belgium. A fellow of the Flanders Research Organization, Debora begins a four-month stage aiming to create peptidomimetic hybrids of G-protein coupled receptor ligands for treating pain. 

• Justin has participated to the Tournois Français des Chimistes in Lyon, France : https://nouvelles.umontreal.ca/article/2024/04/17/premiere-participation-du-quebec-au-tournoi-francais-des-chimistes/ .

• Check out Bill and Yann publication, The Molecular Marvel of the Transformers : https://www.chemistryviews.org/the-molecular-marvels-of-the-transformers/ !

• Preview our review, “Preventing Preterm Birth: Exploring Innovative Solutions” in Clin. Perinatol: https://www.perinatology.theclinics.com/inpress .

• Please note our publication on pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2 using a cluster of differentiation 36 receptor modulator in Frontiers in Pharmacology (DOI: 10.3389/fphar.2024.1303342) .

2023​​​

• Congratulations to Yousra for being distinguished with the 3rd best poster award at the 12th annual Journée scientifique du Groupe de recherche universitaire sur le médicament (GRUM) !

• Kajumee, Nassim, Xiaozheng, and Yousra will present posters at the GRUM 2023 Symposium, while Charity will be giving an oral presentation .

• Congratulations to Sarah-Maude Harvey, who was distinguished with first prize in the inaugural Undergraduate Research Stage Poster Competition, «Concours d’affiches des stages de recherche » of the Chemistry Department (UdeM) for her poster entitled “Synthesis of 1,3,5,8-Tetrasubstituted 1,3,4-Benzotriazepin-2-ones as Urocontrin Peptidomimetics” . 

• Undergraduates Sarah-Maude Harvey and Juan Camilo Fonseca will be present posters at the inaugural Undergraduate Research Stage Poster Competition of the Chemistry Department (UdeM) .

• Congratulations to Kajumee, who received the Grand'Maison Medicinal Chemistry Award !

• Congratulations to Yousra, who received the André-Beauchamp Award for excellence in teaching !

• Take a look at Xiaozheng et al's publication on Urotensin II Receptor Modulation with 1,3,4-Benzotriazepin-2-one Tetrapeptide Mimics in the Journal of Medicinal Chemistry (DOI: 10.1021/acs.jmedchem.3c01307) .

• Check out the publication by Minh Tao et al's on Systematic Exploration of Functional Group Relevance for Anti-Leishmanial Activity of Anisomycin in Biomedicine (DOI : 10.3390/biomedicines11092541) .

• 1 member joined the lab !​​​​

• Ali will start his professional career at NuChem Science, congratulations !​

• Juan and Nassim will be presenting at the 2023 CGCC Symposium .

• Nassim, Charity, Yousra and Xiaozheng will be presenting at the 28th American Peptide Society Meeting !

• 1 member joined the lab .

• Bill, Xiaozheng and Charity will be presenting at the 2023 Canadian Society of Chemistry Meeting .

• Congratulations to Juan for winning a CGCC Undergraduate fellowship !

• Congratulations to undergraduate students Sarah and Justin for winning an NSERC fellowship !

• Congratulations to junior college student Juan, who will pursue his undergraduate study in chemistry at McGill University !

• 4 members joined the lab .

 2022

• Congratulations to Kajumee for passing her comprehensive !

• Check out Xiaozheng, Antoine and Bill's publication on tetrasubstituted benzotriazepinone adopting β-Turn conformation without stereogenic carbon center in The Journal of Organic Chemistry (DOI : 10.1021/acs.joc.3c00113) .

• Check out this media coverage on our Anti-amyloid macrocyclic peptides from Israel21C “Treatment for very early Alzheimer’s under development" https://www.israel21c.org/treatment-for-very-early-alzheimers-under-development/

• Check out this media coverage on our Anti-amyloid macrocyclic peptides from Pscyhologs "A study found new hope for the treatment of Alzheimer's disease" https://www.psychologs.com/article/a-study-found-new-hope-for-the-treatment-of-alzheimers-disease

• Check out this media coverage on our Anti-amyloid macrocyclic peptides from Science Daily  "Promising treatment for Alzheimer's disease” https://www.sciencedaily.com/releases/2023/02/230206104118.htm

• Our manuscript on "Aza-Residue Modulation of Cyclic D,L-α-Peptide Nanotube Assembly with Enhanced Anti-Amyloidogenic Activity" has been published in J. Med. Chem. (DOI : 10.1021/acs.jmedchem.2c02049) .

• Congratulations to Minh Tao for successfully defending her thesis !

• Congratulations to alumni Yann Brouillette for winning the Beaumier Award for High School/CÉGEP Chemistry Teachers ! Check out : https://www.dawsoncollege.qc.ca/news/uncategorized/happy-chemist-yann-brouillette-wins-national-award-for-excellence-in-teaching-chemistry/?fbclid=IwAR3nnjjqFSLh0Ok84Yo0yF2wU7fHTVSOVhfsi0kA0f1nU5Yk2IY0Wm4VOx0

• Ali, Darince, Xiaozheng and Nassim will be presenting at the Journée Carrière 2023. Bill will be at the networking event for students & professors .

• Our manuscript, "The Molecular Marvels of Hulk and She-Hulk" is among "The Content you Liked Best of 2022" in ChemistryViews (DOI :10.1002/chemv.202200012)! Check out : https://www.chemistryviews.org/the-content-you-liked-best-in-2022/ !

• Our manuscript on Early diagnosis and treatment of Alzheimer’s disease has been published in PNAS (DOI : 10.1073/pnas.2210766119) !

• Congratulations to Minh Tao for successfully defending her thesis !

• Congratulations to Charity for receiving the Grand'Maison Award for medicinal chemistry !

• Check out this publication on Pharmacodynamic characterization of rytvela has been published in the American Journal of Obstetrics and Gynecology (DOI : 10.1016/j.ajog.2022.10.007) .

• Our manuscript on Synthesis of 5- and 7-hydroxy indolizidin-2-one has been published in Molecules (DOI : 10.1002/psc.3455) !

• Ali will be presenting at the 1st Meeting of the International Society for Bioactive Peptides (ISBAP) and The 15th International Symposium on VIP, PACAP .

• Our manuscript on Prostaglandin F2α and angiotensin II type 1 receptors has been published in the Journal of Biological Chemistry (DOI : 10.1016/j.jbc.2022.102294) .

• Congratulations to Nassim for winning the best poster award at the 1st Omega Chem Symposium!

• Congratulations to Chitra for passing her comprehensive !

• Bill, Minh Tao & Nassim will be presenting at the 36th European Peptide Society Meeting .

• Congratulations to Charity for passing her comprehensive !

• Congratulations to Koti for successfully defending his thesis !

• Check out Bill's editorial published in Biomedicine (DOI : 10.3390/biomedicines10082037) .

• 1 member joined the lab, welcome .

• Bill, Xiaozheng and Nassim will be presenting at the 27th American Peptide Society Meeting .

• Check out our Mini-review on N-Amino-imidazol-2-one published in synthesis (DOI : 10.1055/s-0040-1719862) !

• Check out our chapter on Ring-closing metathesis/transannular cyclization published in Peptide and Peptidomimetic Therapeutics (DOI : 10.1016/B978-0-12-820141-1.00029-7) .

2022

• Our paper on The Molecular Marvels of Hulk and She-Hulk has been published in ChemistryViews (DOI :10.1002/chemv.202200012)!

• Congratulations to Nassim for passing his comprehensive !

• Congratulations to Koti for publishing in molecules !

• 9 members joined the lab, welcome !

• Nassim, Charity, Ali, Koti, Yousra and Minh Thao will present at 25th Quebec-Ontario Mini-Symposium for Synthetic and Bioorganic Chemistry !

• Nassim, Charity, Ali, Koti, Yousra and Minh Thao will present at the 58th Japanese Peptide Symposium!

2021

• 3 new member joined the lab

• Mrs. Nguyen, Mrs. Luwawa, Mrs. Hamdane and Mr. Mulamreddy will present at The First Canadian Peptide and Protein Community Virtual Symposium !

• Congratulations to Zoé for her CCVC fellowship !

• Congratulations to Charity for her FRQNT fellowship !

• 1 new member joined the lab

• Congratulations to Nassim for his NSERC fellowship !

• 1 new member joined the lab 

2020

• Congratulations to Nassim for his André-Beauchamp award !

• Minh Tao and Yousra will present at The U of Ottawa Centre for Chemical and Synthetic Biology 5th annual Chemical and synthetic Biology Days Talk !

• 1 new member joined the lab

• We moved to MIL Campus !

• Congratulations to Julien to have successfully defended his thesis !

• Congratulations to Cynthia to have successfully defended her thesis !