Professor William D. Lubell

Département de Chimie                                                                                                                                         

Université de Montréal                                                                                                                                             

C. P. 6128 Succursale Centre Ville                                                                                                                           

Montréal, Québec H3C 3J7 CANADA                                                                                                                   

Tel:  514-343-7339                                                                                                                                                   

fax: 514-343-7586

Email: william.lubell@umontreal.ca

 

    Professor in the department of chemistry at the Université de Montréal, I am actively investigating solution-phase and solid-phase synthesis of heterocycles, amino acids, peptides, peptide mimics and the preparation of their libraries by combinatorial science. My interests lie both in developing new methodology for effectively synthesizing these novel structures for drug discovery, as well as in their use to explore protein folding, molecular recognition and bioorganic catalysis.

 

Education

1984:           A.B., Chemistry, Columbia University, NYC, NY, USA

1989:           Ph.D., Professor H. Rapoport, Department of Chemistry, University of California, Berkeley, USA, Thesis Title: "Alpha Amino     

                    Carbonyl Compounds, Synthesis of the Cyclosporine MeBmt Amino Acid."

1990-91:      Postdoctoral Fellow, Professor R. Noyori, Department of Chemistry, University of Nagoya, Nagoya, Japan

 

Academic Positions

04-06 - present: Full Professor – Chemistry – Université de Montréal, Canada

97-06 - 04-05: Associate Professor – Chemistry – Université de Montréal, Canada

91-09 - 97-06: Assistant Professor – Chemistry – Université de Montréal, Canada

90-02 - 91-07: Postdoctoral Fellow – Chemistry – University of Nagoya, Japan

89-11 - 90-01: Postdoctoral Fellow – Chemistry – University of California, Berkeley, USA

85-07 - 89-10: Research Assistant/Teaching Assistant – Chemistry – U. of California, Berkeley, USA

83-06 - 83-08: Undergraduate Research Assistant w/Prof. G. Stork, Chemistry, Columbia U., NY, USA

82-06 - 82-08: Undergraduate Research Asst. w/Prof. R. Breslow, Chemistry, Columbia U., NY, US

 

Awards and Distinctions

2018: Teva Canada Limited Biological and Medicinal Chemistry Lectureship Award of the Canadian Society for Chemistry

2013: Bernard Belleau Award of the Canadian Society for Chemistry for distinguished contribution to the field of medicinal chemistry

2005: Agora Trophy of the Abassadors' Club of the Société du Palais de congrès de Montréal

2002: Merck Frosst Centre for Therapeutic Research Award

1999: Danish National Bank Housing Award: 18 Nyhavn, Copenhagen, Denmark

1997: DuPont Canada, Educational Aid Grant

1994: Bio-Méga/Boehringer Ingelheim Young Investigator

1993 to 1996 : : Ichikizaki Fund for Young Chemists

1990: Monbushu Grant in Aid

1990-1991: Postdoctoral Fellowship, Japan Society for the Promotion of Science

 

Activities and contributions: Selected Appointments

2020/11 – Present: Journal Handling Editor, Amino Acids (Springer)

2019/10 – Present: Editorial Board Member, Molecules (MDPI)

2019/07 – 2019/08: Wilsmore Fellow, University of Melbourne

2018/11 – Present: Editorial Board Member, Biomedicines (MDPI)

2017/05 – 2017/05: Visiting Professor, Department of Chemistry, Universita Degli Studi, Bologna, Italy

2016/05 – Present: Founding Scientist, Mperia Therapeutics Inc.

2016/05 – 2016/06: Schulich Visiting Professorship, Technion - Israel Institute of Technology

2014/07 – 2014/09 : Invited Professor, Université Cergy-Pontoise, Paris, France

2013/08 – Present: Review Editor, Frontiers in Chemical Biology

2013/05 – 2013/06 : Invited Professor, Université Pierre et Marie Curie, Paris, France

2011 – 2015: Member, American Peptide Society, Nominating Committee (elected)

2011/01 – Present: Editorial Board Member, Journal of Peptide Science

2009 : Murray Goodman Award Selection Committee Chair, American Peptide Society

2008 – Present: Editorial Board Member, International J. Peptide Research and Therapeutics

2007: Co-Chair, 20th American Peptide Society Meeting, Montreal

2006/01 - 2006/12: Visiting Professor, Dept. of Chemistry, Dalhousie University, Halifax, Canada

2005/10 – 2018/12: Associate Editor, American Chemical Society, Organic Letters

2005 – Present: Editorial Board Member, Chemical Biology and Drug Discovery

2005 – 2008: Editorial Board Member, J. Peptide Research

2004 – Present: Editorial Board Member, Biopolymers, Peptide Science

2003/06 - 2009/06 : Council Member, American Peptide Society (elected)

1999/02 - 2000/01: Guest Professor, Department of Chemistry, Carlsberg Laboratorium, Denmark

 

Other Professional Activities

2020 : Member, Akabori Memorial Award Selection Committee, Japanese Peptide Soc.

2020 – 2021 : Guest Editor, Special Issue " A Tribute … in Honour of S. Hanessian " Molecules

2020 – 2021 : Guest Editor, Special Issue "Peptide-Based Drug Development" Biomedicines

2019 – 2021 : Scientific Advisory Board Member, 36th European Peptide Symposium, Barcelona,

Spain 08/21

2018 – 2020 : Research Topic Editor “Polyamide Backbone Modification in Peptide and Protein Science” Frontiers in Chemistry

2018 – 2020 : Co-Organizer, Peptide Science Symposium, PACIFICHEM, Honolulu, HA, 12/20

2018 – 2019 : Co-Organizer, Peptide Science Symposium 102nd CSC, Quebec City, 06/19

2017 – 2018 : Invited Editor, “Peptide Science” special issue “Emerging Peptide Science from Canada”.

2017 – 2018 : Scientific Advisory Board Member, Peptide Meeting in Tenerife 5-6 March 2018

2017 – 2018 : Co-Organizer, Peptide Science Symposium, 101st CSC, Edmonton, 05/18

2017 – 2018 : Scientific Advisory Board Member, 35th European Peptide Symposium, Dublin,

Ireland 08/18

2016 – 2017 : Co-Organizer, Peptide Science Symposium, 100th CSC, Toronto 05/17

2016 : Member, Merrifield Award Selection Committee, American Peptide Society

2016 – 2017 : Scientific Advisory Board Member, 34th European Peptide Symp. and 8th

International Peptide Symp., Leipzig, Germany 09/16

2015: Invited co-editor, “Peptide Science” special issue “Peptides in Paris”

2013 – 2015 : Co-Organizer, Peptide Chemistry Symposium, PACIFICHEM, Honolulu, HA, 12/15

2013 – 2014 : Co-Organizer, Peptides in Paris Symposium, PIPS 2014, Paris 10/14

2013 – 2014 : Co-Organizer, Peptide Science Symposium, 97th CSC, Vancouver 05/14

2012 – 2013 : Co-Organizer, Peptide Science Symposium, 96th CSC, Quebec City 05/13

2012 : Editor of Am. Chem. Soc. virtual issue “Peptide Chemistry”

2012 – 2013 : Chair, Biological & Medicinal Chem. Division, Canadian Society of Chemistry

2011 – 2012 : Treasurer, Biological & Medicinal Chem. Division, Canadian Society of Chemistry

2010 – 2011 : Organizer, Biol. & Med. Chem. Division Symposia, 94th CSC, Montreal 06/11

2010 – 2011 : Organizer, Peptide Science Symposium, 94th CSC, Montreal 06/11

2010: Member, 22nd American Peptide Society Meeting, Scientific Program Committee

2009 – 2010 : Co-organizer, Peptide Chemistry Symposium, PACIFICHEM, Honolulu, HA, 12/10

2009 : Member, Scientific Program Committee, 5th Int. Peptide Symp. and 47th Japanese Peptide Symp., Kyoto, Japan, Dec. 4-9, 2010

2009 : Organizer, Am. Chem. Soc. Hirschmann Award Symp., Salt Lake City, UT, USA

2008 – present : President, VW2L Consultants Inc. 2006 – present: Originator and Director, Molecules of Life (MoL, www.moleculesoflife.ca)

2006 – 2015 : Director, Montreal Centre for Combinatorial Chemistry (MC3)

2005 – 2006 : Organizer, Peptide Science Symposium, 89th CSCCE, Halifax, NS 06/06

2005 – 2012 : Founding Board of Directors Member and Chemistry Representative, GRUM, Groupe de recherche universitaire sur le medicament, Université de Montréal

2005 – 2011 : Board of Directors Member and Team Chemist, CTiGAR, CIHR-funded Team in G Protein-Coupled Receptor Allosteric Regulation

2004 – 2005 : Co-organizer, Peptide Chemistry Symposium, PACIFICHEM, Honolulu, HA, 12/05

2004 : Member, 19th American Peptide Society Meeting, Scientific Program Committee

2002 – 2007 : Vice-president, VW2L Consultants Inc.

2002 : Member, 2003 Bruce Merrifield Award Nominating Committee, Am. Peptide Society

2002 : Member, 18th American Peptide Society Meeting, Scientific Program Committee

2002 – 2006 : Director, Québec Combinatorial Chemistry Consortium (QC3)

2000 – 2001 : Organizer, Combinatorial Chemistry Symposium, 83rd CSCCE, Montreal 06/01

1999 – 2000 : Co-organizer, Peptide Chemistry Symposium, PACIFICHEM, Honolulu, HA, 12/0

Invited Conference Presentations / Keynote and Plenary Lectures

65. 36th European and 12th International Peptide Symposium, Barcelona, Spain, 29/08-3/09, 2021.

64. Oxford Global, 8th Peptides Congress, 04, 26–27, 2021

63. 8th Biennial Indian Peptide Symposium (IPS-2021) Indian Inst. Sci., Bangalore, 03, 24-26, 2021.

62. 7th Modern Solid Phase Peptide Synthesis Symposium. Palm Cove, Australia, 5-7 Sep. 2019

61. 26th American Peptide Symposium, Monterey, CA, USA, June 22-27, 2019.

60. Endocrine Society Meeting ENDO2019, New Orleans, USA, March 23-26, 2019.

59. Peptide Therapeutics Forum, Basel, Switzerland, September 13-14, 2018.

58. 35th European Peptide Symposium, Dublin, Ireland, August 26-31, 2018.

57. 101st Can. Chem. Conf., Teva Canada Ltd BMC Award Lecture Edmonton, AB May 27-31, 2018

56. Peptide Meeting in Tenerife, 5-6 March 2018

55. CHI’s Peptide Discovery and Delivery Conference, Boston, USA, March 26-27, 2018.

54. 4th Belgian Peptide Group Meeting, Brussels, Belgium, February 28th and March 1st, 2018.

53. 16th Iberian Peptide et 4th Chem. Biology Group Meeting, Barcelona, Spain, Feb. 5-7, 2018.

52. 25th American Peptide Symposium, Whistler, BC, June 17-22, 2017.

51. 34th European and 8rd International Symposium on Peptides, Leipzig, Germany, Sept. 4-9, 2016.

50. 15th Belgium Organic Synthesis Symposium, Antwerp, Belgium, July 10-15, 2016.

49. 15th Naples Workshop on Bioactive Peptides, Centro Congressi Federico II, Italy, June 23-25, 2016.

48. Chemical Biology Symposium, Technion-Israel Institute of Technology, Israel, May 29, 2016.

47. 24th American Peptide Symposium, Orlando, FL, USA, June 20-25, 2015.

46. Distinguished Philips Visitor Haverford College Lectures, Haverford, PA, USA, Dec. 4-5, 2014

45. 14th Naples Workshop on Bioactive Peptides, Centro Congressi Federico II, Italy, June 12-14, 2014.

44. Pacific Northwest Biological Chemistry Volcano Conference, Pack Forest, WA, USA, Jan. 3, 2014.

43. 96th Canadian Chemistry Conf., Bernard Belleau Award Lecture, Québec City, QC, May 30, 2013.

42. 18ème Congrès du Groupe Français des Peptides et des Protéines, Sète, France, May 26-31, 2013.

41. The Peptide Chemistry Conference, Riviera Maya, Mexico, Nov. 2-6, 2012.

40. 1st UdeM-MANA workshop on Nano-Life, University of Montreal, Montreal, QC, July 19, 2012

39. 22nd American Peptide Symposium, San Diego, CA, USA, June 25-30, 2011.

38. Frontiers in Peptide Science, PACIFICHEM 2010 - Honolulu, HA, USA, Dec. 18-19, 2010.

37. 5th International Peptide Symposium and 47th Japanese Peptide Symp. Kyoto, Japan, Dec. 4-9, 2010

36. 31st European Peptide Soc. Meeting, Copenhagen, Denmark, Sep. 5-9, 2010.

35. Swedberg Lecture, Uppsala U., Uppsala, Sweden, Aug. 30, 2010.

34. XIX Biennial Meeting of the International Society for Eye Research, Montreal, QC, Jul. 18-23, 2010

33. 13th Int. IUPAC Polymer & Organic Chemistry, Montréal, QC, Jul. 5-9, 2009.

32. Am. Chem. Soc. Hirschmann Award Symp., Org. Chem. Div., Salt Lake City, USA, Mar. 2009.

31. Peptides 2007, Australian Peptide Soc. Meeting, Cairns, Australia, Oct. 2007.

30. 89th Canadian Society of Chemistry Conference, Halifax, NS, May 27-31, 2006.

29. Gordon Res. Conference, Peptides, Ventura, CA, USA, Feb. 2006.

28. PACIFICHEM 2005, Honolulu, HA, USA, Dec. 15-20, 2005.

27. 19th American Peptide Symposium, San Diego, CA, USA, Jun. 18-23, 2005.

26. Boeheringer Ingelheim Lecture, University of British Columbia, BC, Mar. 2005.

25. 28th European and 3rd International Symposium on Peptides, Prague, CZ, Sep. 5-10, 2004.

24. Acfas colloquium "chimie combinatoire et biologie", UQAM, Montreal, QC, May 12, 2004.

23. IUPAC/CSC meeting, Ottawa, ON, Aug. 10-15, 2003.

22. 18th Am. Peptide Symp., Boston, MA, Jul. 19-23, 2003.

21. Am. Chem. Soc., Hirschmann Award Symp., Med. Chem. Div., New Orleans, LA, USA, Mar. 2003.

20. IUPAC/CSC Meeting, Ottawa, ON, Aug. 10-15, 2003.

19. Merck Frosst Centre, Therapeutic Res. Award Lecture, 85th CSC Vancouver, BC, Jun. 1-5, 2002.

18. 85th CSC Vancouver, BC, Jun. 1-5, 2002.

17. 17th Am. Peptide Symp., San Diego, CA, USA, Jun. 9-14, 2001.

16. 69th Congrès de l'Acfas, U. Sherbrooke, Sherbrooke, QC, May, 16, 2001.

15. Am. Chem. Soc. Hirschmann Award Symp., Med. Chem. Div., San Diego, CA, USA, Apr. 3, 2001.

14. Symposium on Antibiotics, Pacifichem 2000, Honolulu, HA, USA, Dec. 14 – 19, 2000.

13. Gordon Research Conference Heterocycles, Newport, RI, USA, Jul. 4-8, 2000.

12. Mini-symposium on Natural and Non-Natural Products, U. Hamburg, Germany, Dec. 6-7, 1999.

11. Mini-workshop Biophys. Biomol. Modeling, Technical U. Denmark, Lynby, DK, Sep. 17, 1999.

10. Peptidomimetics Symp., Houffalize, Belgium, Apr. 26-03, 1999.

9. 81st CSCCE, Whistler, BC, May 31 – Jun. 4, 1998.

8. 5th Chem. Congr. N. Am., Cancun, Mexico, Nov. 11-15, 1997.

7. 2nd Can. Conf. Combi. Chem., Montreal, QC, Oct. 6-7, 1997.

6. 64e Congrès de l'Acfas, McGill U., Montreal, QC, May 14, 1996.

5. IBC's 3rd Annual Conference Peptidomimetics, Washingto, DC, USA, Mar. 6-8, 1996.

4. 78th CSCCE Conf., U. of Guelph, Guelph, ON, May 28 – Jun. 1, 1995.

3. Ottawa-Carleton Chemistry Institute 25th Spring Synthesis Symposium, Ottawa, ON, May 1, 1995.

2. 62nd Congrès de l'Acfas, UQAM Montreal, QC, May 16-20, 1994.

1. 2nd Canadian Workshop on Organic Synthesis, Jouvence, QC, May 25-28, 1993.